Wtip and Vangl2 are required for mitotic spindle orientation and cloaca morphogenesis
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چکیده
منابع مشابه
Wtip and Vangl2 are required for mitotic spindle orientation and cloaca morphogenesis
Defects in cilia and basal bodies function are linked to ciliopathies, which result in kidney cyst formation. Recently, cell division defects have been observed in cystic kidneys, but the underlying mechanisms of such defects remain unclear. Wtip is an LIM domain protein of the Ajuba/Zyxin family, but its role in ciliogenesis during embryonic development has not been previously described. We re...
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ژورنال
عنوان ژورنال: Biology Open
سال: 2012
ISSN: 2046-6390
DOI: 10.1242/bio.20121016